Different T cell memory in preadolescents after whole-cell or acellular pertussis vaccination
نویسندگان
چکیده
منابع مشابه
Whole-cell and acellular pertussis vaccines.
OBJECTIVE To provide a review of pertussis vaccines, including information on efficacy, adverse reactions, and antibody production following administration of both whole-cell and acellular pertussis vaccines. DATA SOURCES A MEDLINE search and extensive review of journals was conducted to identify the information for this review. DATA EXTRACTION Pertinent studies reporting experience with pe...
متن کاملWhole-cell and acellular pertussis vaccination programs and rates of pertussis among infants and young children.
BACKGROUND The transition from a whole-cell to a 5-component acellular pertussis vaccine provided a unique opportunity to compare the effect that each type of vaccine had on the incidence of pertussis, under routine conditions, among children less than 10 years of age. METHODS Analyses were based on passive surveillance data collected between 1995 and 2005. The incidence of pertussis by year ...
متن کاملPertussis-specific cell-mediated immunity in infants after vaccination with a tricomponent acellular pertussis vaccine.
The aim of this study was to investigate pertussis-specific cell-mediated immunity in infants vaccinated with a tricomponent acellular vaccine. Infants were investigated during a primary vaccination schedule from the third month of life to the sixth month as well as before and after a booster at 15 to 24 months. This is the first report of specific cell-mediated immune responses to pertussis-re...
متن کاملUnexpectedly limited durability of immunity following acellular pertussis vaccination in preadolescents in a North American outbreak.
BACKGROUND Despite widespread childhood vaccination against Bordetella pertussis, disease remains prevalent. It has been suggested that acellular vaccine may be less effective than previously believed. During a large outbreak, we examined the incidence of pertussis and effectiveness of vaccination in a well-vaccinated, well-defined community. METHODS Our center provides care to 135 000 patien...
متن کاملWhole-Cell or Acellular Pertussis Primary Immunizations in Infancy Determines Adolescent Cellular Immune Profiles
Introduction Pertussis is re-emerging worldwide, despite effective immunization programs for infants and children. Epidemiological studies show a more limited duration of protection against clinical pertussis in adolescents primed with acellular pertussis (aP) vaccines during infancy than those who have been primed with whole-cell pertussis (wP) vaccines. This study aimed to determine whether m...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2013
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2013.10.056